Exon 1被通过同源重组替换为neo cassette, Western blot结果显示,纯合小鼠视网膜中没有蛋白表达。(来源:J:150490)
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Exon 1 was replaced with a neo cassette via homologous recombination. Western blot analysis confirmed the absence of protein expression in the retinas from homozygous mice. (J:150490)