germ line(生殖细胞)、Cre介导的重组允许表达一个修改后的第5外显子,其中所有6个细胞内的酪氨酸都被苯丙氨酸替换,且最后一个缬氨酸被删除。预测其产物将不具备细胞内信号传递的能力。(来源:J:150043)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion, Nucleotide substitutions
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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