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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Mrgprd
tm3(DTA)Mjz
Alias:
Mrgprd
DTA
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基础信息
表型特征
文献报道
开放阅读框被替换为rtTA和IRES-EGFP,接着是tet操作子和链霉素抗性决定子(diphtheria toxin基因)。链霉素抗性毒素在不含doxycycline的情况下表达,从出生起就导致Mrgprd+神经元的消除。(来源:J:149999)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3849869
Not Specified
Targeted
插入,基因内删除
--
1
--
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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