Log In|Sign Up
中文
Exon 2被替换为一个经过A到G的转换，导致第42位的Arginine被Lysine替换（K42R）。这种突变通过酶学测定证实，使得蛋白产物失去了激酶活性。在ES细胞中，通过暂时的Cre表达移除了下游的floxed neo cassette（来源：J:150046）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
