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中文
将一个IRESCreERT-lox-PGKneo-lox cassette插入Scgb1a1基因座的3' UTR区域。构建好的靶向载体通过电穿孔方式导入129/SvEv小鼠胚胎干细胞进行同源重组。通过囊胚注射，重组的ES细胞产生了嵌合体。随后，通过与Gt(ROSA)26Sortm1(FLP1)Dym (FLPeR)小鼠杂交，删除了PGK-neo cassette。Scgb1a1基因座的Cre表达通过给予他莫昔芬诱导。来源：(J:149822)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
