Myocd基因的1号外显子编码区域通过同源重组被一个包含cre重组酶序列和Frt标记的neo cassette替换,这样内源性Myocd启动子驱动cre的表达。之后,通过与Flpe转基因小鼠杂交移除了neo cassette(来源:J:149882)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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