一个带有floxedNeo标记的诺卡因 cassette 替换了包括V5基因段和V5基因段与TEA启动子之间间隔序列的4kb基因序列。通过Cre介导的neomycin cassette的删除,去除了V5基因段,将TEA启动子的位置与V5基因段相同。南方 blotting确认了靶向的正确性。(来源:J:149413)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129
Targeted
基因内删除
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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