germ line(生殖线)、由Cre介导的重组移除了带有floxed neo和STOP cassette的等位基因。这个突变体在OTT-MAL(一种二十-two-megakaryocytic急性白血病患者)中表达出与t(1;22)(p13;q13)染色体易位相关的融合蛋白。(来源:J:149622)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count