germ line(生殖线)、由Cre介导的重组移除了带有floxed neo和STOP cassette的等位基因。这个突变体在OTT-MAL(一种二十-two-megakaryocytic急性白血病患者)中表达出与t(1;22)(p13;q13)染色体易位相关的融合蛋白。(来源:J:149622)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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