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中文
在exon 4上游插入了一个带有loxP座的neo质粒，exon 5下游也增加了一个loxP位点。通过短暂表达cre重组酶，neo质粒被剔除，使得exons 4和5成为可调节的。exon 4编码的DSL区域在不同物种中都有保守性，且对于配体受体交互至关重要。cre重组酶对exon 4和5的缺失预测会导致帧移突变，并在192个氨基酸后导致蛋白质提前截断。(来源：J:149131)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
