这个基因陷阱载体包含了β-geo cassette,它被插入在第六外显子下游。通过 Western blot 对杂合子小鼠的线粒体蛋白样本,我们确认了蛋白表达量的下降。(来源:J:149173)
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The gene trap vector, containing a beta-geo cassette, inserted downstream of exon 6. The reduction in protein expression was confirmed by western blot analysis mitochondrial protein samples from heterozygous mice. (J:149173)