人类细菌人工染色体(BAC)库(chori)被用来获取一个188kb的BAC,它包含了整个人类LRRK2(Leucine-rich repeat kinase 2)基因,包括基因起始点前29kb和终止点后42kb的区域。生物信息学分析显示,BAC中没有其他基因。这个BAC随后被注入了FVB/NTac受精卵中。(来源:J:149135)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NTac
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1
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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