构建了一个含有SMN(A111G)错义突变的转基因,由4.1kb的SMN启动子控制,这个转基因被注入了FVB/N小鼠的受精卵中。获得了10个祖先系,随后建立了线588。这个系被发现含有5个转基因拷贝。(来源:J:148541)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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