这个转基因表达的是人类的STAT6基因,其中V625和T626位点的密码子被修改为Alanine,并在CD2调控区的驱动下带有C端的FLAG标签。该启动子限制了转基因在主要针对B和T淋巴细胞的表达。除了78号克隆,还建立了24号创始克隆。(来源:J:133480)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3H
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1
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15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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