在编码孔道α亚基的外显子上游插入了一个Loxp位点,通过同源重组方式在下游插入了带有floxed neo-TK cassette。随后,通过Cre介导的重组移除了neo cassette,使得该外显子被留了下来。(来源:J:91427)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
5
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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