这个构建包含一个剪接接受位点、一个带有neo-stop cassette的可调节Nfatc2基因、一个Frt flank的IRES-GFP cassette,通过同源重组插入了内皮1号染色体。可调节的Nfatc2基因有钙调素结合位点的突变,使其对配体的亲和力增强。突变蛋白序列为HPVIVITGP。(来源:J:148341)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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