这个转基因载体包含了增强型绿色荧光蛋白(EGFP)的编码序列,后面跟着一个polyadenylation信号,插入到了小鼠基因组的细菌人工染色体(BAC)RP23-130H21的Septin 6(Sept6)基因的起始转录密码子位置。这样,报告基因的mRNA/蛋白质表达由小鼠基因的调控序列驱动。(来源:J:100256)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NTac
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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