Tlr9^M5Btlr

This mutation, discovered in an in vivo CpG challenge screen of progeny of an ENU mutagenized male mouse, comprises a G to A transition at nucleotide position 3188, in the second and last exon of the gene, that results in replacement of glycine by arginine at amino acid position 1028 of the receptor protein (Q1028R). (J:86521, J:147856)