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中文
通过在原位插入工程点突变，去除了Acetyltransferase(AT)的活性。这些突变用异亮氨酸(Alanine, A)和丝氨酸(Serine, S)替换色氨酸(Trp, W)和酪氨酸(Tyr, Y)，具体位置是1466-1477的WY。这个突变型被用来构建Ep300tm1Reck这个基因工程品。(来源：J:85950)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
