Ihh^tm1.1Dcha

A 397G>A substitution was introduced into exon 1 and a floxed neo cassette was inserted into intron 1 via homologous recombination. Cre mediated recombination then removed the neo cassette leaving a single loxP site in intron 1. The point mutation results in a E95K mutation in the protein. (J:147878)