从3到7号外显子被替换成一个带有IRES-ECFP和neo cassette的序列。免疫组化结果显示 zona fasciculata区域没有蛋白表达。(来源:J:147610)
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Exons 3 through 7 were replaced with an IRES-ECFP and neo cassette. Immunohistochemistry confirmed the absence of protein expression in the zona fasciculata. (J:147610)