设计了一个靶向载体,包含SV40剪接接受器、一个由loxP位点标记的停泊子(包含PGK-neo和三重SV40转录终止序列)、携带家族帕金森病关联E46K突变的人类α-synuclein基因(SYNE46K)以及牛的polyA信号序列。(来源:J:147333, J:150777)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129
Targeted
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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