一段包括3个5'非翻译序列的基因片段,所有是exon 1,以及47个内含子1的序列,被替换为改良后的Cre基因,后面跟着两个串联的SV40polyA序列和一个Frt标记的neo cassette。随后,通过Flp介导的重组移除了neo cassette。(来源:J:152867)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
插入
--
1
4
54

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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