这个向量包含了CAG启动子,驱动一个带有floxed neo/STOP元件的表达,旁边是frt标签的lacZ基因,带有3个polyadenylation序列(作为次要的STOP cassette),以及EGFP基因。这个基因元件被插入到特定的位置。通过小鼠的生殖细胞(germ line)、Cre和Flp的介导重组,可以去除neo/STOP和lacZ/STOP cassette,从而实现EGFP的广泛表达。来源:(J:147304)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
插入
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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