这个向量包含了CAG启动子,驱动一个带有floxed neo/STOP cassette的表达,这个 cassette由frt标签的lacZ基因和3个polyadenylation序列(作为次要STOP cassette)组成,最后是EGFP基因。lacZ的表达依赖于cre介导去除主要的STOP cassette,而EGFP的表达则需要cre去除主要的STOP cassette,并通过flp介导移除次要的STOP cassette。(来源:J:147304)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
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38

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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