Tg(Dazl-EGFP)10Rarp

The Dazl-eGFP transgene was designed with a 1.7 kb mouse Dazl (deleted in azoospermia-like sequence (located upstream of the translational start site that also included the 5' UTR) all upstream of an enhanced green fluorescent protein (EGFP) coding sequence and SV40 polyA sequence. Expression of EGFP is directed primarily to adult mouse testis; muchlower EGFP transcript and fluorescence is observed in adult ovaries. Very low levels of EGFP transcript expression (but not fluorescence) are reported in fetal and newborn gonads of both sexes. (J:146882)