这个转基因包含了全长的编码C末端带有六 histidine 标签的mouse ADAM3(一种金属肽酶和整合素样结构域3,cyritestin)的cDNA,后面跟着牛血红蛋白的polyadenylation序列,由mouse calmegin基因的特异性启动子控制表达。 Western blot结果显示,Adam3tm1Ihig纯合子小鼠的睾丸和精子中都检测到了ADAM3。(来源:J:147330)
Basic Information
129S1/Sv and 129X1/SvJ and CD-1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count