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中文
Exon 2被替换为一个自我剪切的neo和cre cassette，通过同源重组实现。在通过雄性生殖细胞系传递时，neo和cre cassette会被剔除，留下一个loxP位点。RT-PCR和 Western blot的结果证实了纯合小鼠组织中没有完整转录本和蛋白表达(来源：J:146487)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
