在对C57BL/6J小鼠的创始株进行多剂量N-乙基-N-亚硝基脲(ENU)处理以诱导突变后,检测到myostatin(Mstn)基因的第二个内含子,在距第二个外显子两个碱基下游的第二位置发生了T到C的转换(这是一个在几乎所有脊椎动物内含子中保守的剪接供位)。(来源:J:146513)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
隐性
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部