将一个带有终止密码子的单克隆RFP基因片段,作为floxed形式,置于GFP报告基因上游。这个转基因通过鸡肌动蛋白普遍驱动元件(actin promoter)进行调控。当Cre重组酶表达时,mRFP-停泊子被剔除,GFP表达则由CAG启动子驱动。(来源:J:146140)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count