这个转基因包含了完整的编码小鼠ADAM3(一种金属肽酶和整合素样域3,cyritestin)的cDNA,后面跟着牛的 globin polyadenylation 启动子,并在小鼠calmegin基因的特异性睾丸启动子驱动下表达。 Western blot 实验显示,Adam3tm1Ihig纯合子小鼠的睾丸和精子中都检测到了ADAM3。(引用:J:147330)
Basic Information
129S1/Sv and 129X1/SvJ and CD-1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count