在exon 15的上游XbaI位点插入了loxP位点,另一个XbaI位点下游则插入了loxP和含FRT标签的诺卡因抗性基因座。通过与FLPe重组酶转基因小鼠杂交,移除了诺卡因基因座。这个被修复的exon编码了蛋白质产物的VII和VIII个激酶亚基。(来源:J:145923)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
1
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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