在 intron 1 中插入了一个含 frt 和 loxP 标记的neo cassette,然后通过同源重组在 intron 2 中插入了第三个 loxP 立场。通过 Cre 引导的重组移除了neo cassette,使得 exon 2 成为可删除的。(来源:J:145744)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
1
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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