人类AURKA基因(Aurora-A)的编码序列被置于小鼠乳腺癌病毒增强子和启动子的控制下。通过构建的转基因载体,建立了6个克隆系,其中表达最高的两个品系被合并用于表型分析。转基因在乳腺和唾液腺的表达最高,其次是(按表达量降序)肾、脾、肝、脑和子宫。(来源:J:145680)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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