germ line(生殖细胞)通过Cre介导的重组技术删除了12到15号外显子。蛋白表达缺失通过在小鼠胚胎成纤维细胞中进行 Western blot 分析得到了确认。(来源:J:145539)
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Germ line, cre mediated recombination was used to remove exons 12 through 15. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:145539)