四环素操纵子被用来驱动一个人类cDNA的诱导表达,这个cDNA的核苷酸序列经过修改,导致第600位的谷氨酸被缬氨酸(V600E)替换。这种突变产生了恒定激活的形式。两条线(29号和13号线)被建立,其中29号线被选作代表线。(来源:J:144358)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
--
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部