在第7外显子编码的锌酶催化中心插入了一个有框停泊点的诺他霉素抗性基因 cassette。这个过程中,目标位点删除了140bp。通过肾转录mRNA的末端 PCR,结果显示无转录发生。尿液免疫印迹分析证实了无蛋白产物。(来源:J:145147)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
--
14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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