Pold1小鼠与表达Tg(Sycp1-cre)1Uchi转基因小鼠杂交。Cre在生殖细胞中的表达会去除SV40的剪接/polyadenylation信号和诺卡因抗性基因座。由此产生的等位基因编码一种3'-5'核酸外切酶活性缺失的蛋白质。(来源:J:144992)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
插入
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1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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