装有lacZ报告基因和一个敲除neo抗性基因的盒式载体,替换了基因座位中2号和3号外显子的部分区域。基因失活通过检测Th17样脾细胞上清液中不可检测到的蛋白质,通过ELISA方法得到了确认(来源:J:144710)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6)F1
Targeted
插入,基因内删除
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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