在18号和19号外显子之间插入了loxP位点,然后在20号和21号外显子间插入了一个1.8kb的DNA片段,这个片段带有另一个loxP位点和frt标记的PGK-neomycin筛选载体。通过与Tg(EIF1A-flp)66Mim小鼠杂交,移除了neomycin选择性 cassette。现在,19号和20号外显子仍被loxP位点所包裹。(来源:J:144994)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
8
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部