将人类神经转化酶的cDNA片段克隆到了小鼠Thy1.2基因表达元件的XhoI位点。在Thy1启动子和神经转化酶起始密码子之间插入了含LoxP标记的转录终止子。这些带有转基因的鼠与持续表达Cre的鼠杂交,目的是删除含LoxP的转录终止子,激活无活动的转基因(来源:J:136579)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
--
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部