在exon 3上游插入了loxP位点,然后将5到6号外显子替换为编码5到14号外显子的cDNA,后面跟着人GH的poly(A)序列、HPRT微基因和另一个loxP位点。10到14号外显子在基因中是重复的,但转录本中没有。(来源:J:144572)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Duplication, Insertion, Intragenic deletion
--
1
6
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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