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中文
将eGFP载体和一个含Neomycin抗性基因的floxed Neo cassette插入基因座外1号非编码区。先验品小鼠与EIIa-cre转基因小鼠杂交，以去除Neo cassette，留下LoxP位点。在杂合子和纯合子小鼠的骨髓细胞中，检测到了GFP表达，特别是在髓系细胞中。在对纯合子小鼠经细胞因子刺激后的骨髓细胞进行免疫印迹时，未检测到内源性蛋白，这证实这是一种无功能基因。(来源：J:144696)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
