germ line(生殖细胞)中,通过Cre介导的重组手段移除了 kalrn7 特有的外显子,通过大脑皮层提取物的 Western blot 分析,确实证实了 kalrn7 和 deltaKalrn7 蛋白表达的缺失。(来源:J:142364)
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Germ line, cre-mediated recombination was used to remove the exon specific for isoform 7. The absence of protein expression of Kalrn7 and deltaKalrn7 was confirmed by western blot analysis of cerebral cortex extracts. (J:142364)