在Kalrn-7特异性外显子上游插入了loxP位点,然后在该外显子下游插入了带有3' loxP标记的frt-flankedneo cassette。通过转基因小鼠的germ line,使用flp介导的重组来去除neo cassette,使得特异性的外显子被去除了。(来源:J:142364)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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