在exon 2的上游插入了一个loxP位点,然后在exon 2的下游插入了一个带有3' loxP座的frt-flankedneo cassette。通过germ线的flp介导重组,移除了neo cassette,使得exon 2成为可删除的(floxed)区域。(来源:J:143476)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count