将cre和人类孕激素受体融合,随后插入一个新 cassette 和包含3到9号外显子的基因序列,这些序列位于3号外显子上游。3到9号外显子被复制。蛋白表达缺失通过脑组织 Western blot 分析得到了确认(来源:J:144537)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
Duplication, Insertion
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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