Log In|Sign Up
中文
设计了一个靶向载体，用于替换目标基因的第一个外显子，替换成含cre cDNA序列和frt座标记的PGK-neo片段。该载体通过电穿孔法导入了129X1/SvJ衍生的RW4胚胎干细胞。杂交胚胎被用来培育突变小鼠。随后，这些突变小鼠与FLPe小鼠（C57背景）杂交，以去除选择性载体。(来源：J:90391)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
