Tg(Neurod2-Smo*A1)199Jols

The ND2:SmoA1 transgene contains the entire mouse smoothened homolog (Drosophila) Smo gene, with the constitutively active point mutation SmoA1 (W539L), driven by the 1kb mouse neurogenic differentiation 2 (Neurod2) promoter. Several lines were generated (lines 199, 193, 234, 255 and 201) with varying levels of expression (30-, 45-, 36-, 2- and 3-fold, respectively, relative to wild0type expression). (J:93861)