在翻译起始点上游66bp的第2外显子的EcoRI位点插入了cre/ERT2载体,同时伴随一个由Frt序列引导的PGK-neomycin筛选 cassette。随后,这些杂合子小鼠与Tg(ACTFLPe)9205Dym背景的鼠进行杂交,以剔除neomycin筛选 cassette。(来源:J:144088)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
2
91

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部