改性鸡β-actin启动子(CAG)被用来驱动一种带有核定位信号和三聚腺苷酸序列的floxed lacZ基因的泛表达。floxed cassette后面跟着一个具有Q227D氨基酸替换(替换为谷氨酰胺)的常激活型人类BMPR1A序列,以及间隔序列和EGFP编码序列。BMPR1A的常激活表达和EGFP依赖于Cre酶。目前无品系信息。(来源:J:143588)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
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1
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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