改性鸡β-actin启动子(CAG)被用来驱动一种带有核定位信号和三聚腺苷酸序列的floxed lacZ基因的泛表达。floxed cassette后面跟着一个具有Q227D氨基酸替换(替换为谷氨酰胺)的常激活型人类BMPR1A序列,以及间隔序列和EGFP编码序列。BMPR1A的常激活表达和EGFP依赖于Cre酶。目前无品系信息。(来源:J:143588)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count